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#11. Combined immunotherapy encompassing intratumoral poly ...

Key words: intratumoral injections, poly-ICLC (Hiltonol), dendritic cell vaccination, radiotherapy and abscopal effects.

#12. poly iclc - My Cancer Genome

A synthetic complex of carboxymethylcellulose, polyinosinic-polycytidylic acid, and poly-L-lysine double-stranded RNA. Poly ICLC may stimulate the release ...

#13. Poly ICLC - Oncovir - AdisInsight

Poly ICLC (Polyinosinic-Polycytidylic acid with Polylysine and Carboxymethylcellulose) is a biological response modifier, that is being developed by Oncovir ...

#14. Poly-ICLC stimulates MDA5 more effectively than poly-IC ...

Download scientific diagram | Poly-ICLC stimulates MDA5 more effectively than poly-IC through the proton sponge effect. a, b The CD8αDC cell line was ...

#15. Nasal Poly-ICLC (Hiltonol®) for SARS-CoV-2 Infection

The Poly-ICLC (Hiltonol®) may help prevent the COVID-19 infection from invading the inside of your nose and spreading to other body structures such as the lungs ...

#16. Poly iclc | Sigma-Aldrich

Find poly iclc and related products for scientific research at ... Poly(vinyl chloride) European Pharmacopoeia (EP) Reference Standard ...

#17. multi-institution phase II study of poly-ICLC and radiotherapy ...

There is limited prior experience with poly-ICLC in glioma and none when combined with TMZ. A pilot study of 38 patients with newly diagnosed or ...

#18. Type I IFN Induction via Poly-ICLC Protects Mice against ...

neoformans (H99) infected mice with poly-ICLC (pICLC), a dsRNA virus mimic. Unexpectedly, pICLC treatment greatly extended survival of infected ...

#19. Method for preparation of poly-iclc and uses thereof - Google ...

Thus, in contrast to conventional antiviral agents such as cidofovir, poly-ICLC could represent an ideal adjuvant to live virus vaccines, especially those such ...

#20. PROCESS FOR PREPARING POLY-ICLC AND USES ...

WONG J P ET AL: "Liposome-mediated immunotherapy against respiratory influenza virus infection using double-stranded RNA poly ICLC", VACCINE, ...

#21. Poly ICLC in the Treatment of Postinfectious Demyelinating ...

Three weeks after a mild and presumably infectious illness, a 21-year-old man developed a CNS disorder characterized by involvement of the cerebellum, ...

#22. Intratumoral (Poly-ICLC) Therapy for Dogs with Advanced ...

We aimed to investigate the clinical efficacy, quality of life, and adverse events of poly-ICLC treatment in dogs with advanced cancers. Our results showed that ...

#23. Enhanced therapeutic efficacy of poly(ICLC) and ribavirin ...

The therapeutic efficacy of polyriboinosinic-polyribocytidylic acid stabilized with poly-L-lysine and carboxymethyl cellulose [poly(ICLC)] ...

#24. 晚期癌症犬的瘤内(Poly-ICLC) 治疗：关于临床有效性 - X-MOL

Polyinosinic-polycytidylic acid-poly-l-lysine carboxymethylcellulose (poly-ICLC) 是一种合成的双链病毒RNA 类似物，作为人类治疗性癌症疫苗的成分和治疗人类癌症 ...

#25. 在根治性全身疾病自体疗法之前使用肿瘤内和（ICLC）对癌症 ...

本研究的目的是测试一种回避自身免疫系统的方法这研究将测试注射一种物质多聚赖氨酸和通过MRI（显微镜显微镜）（Poly-IC、Hiltonol®） 咔嚓咔嚓声响，技术进入锥体。

#26. Toll like receptor-3 ligand poly-ICLC promotes the efficacy of ...

BioMedCentralPage 1 of 15(page number not for citation purposes)Journal of Translational MedicineOpen AccessResearchToll like receptor-3 ligand poly-ICLC ...

#27. Phase I-II Trials of Poly(ICLC) in Malignant Brain Tumor Patients

ABSTRACT Poly(ICLC) preparation, containing poly-L-lysine and poly(I) • poly(C) at a weight ratio of 1:2, was given intravenously at a dose ...

#28. IMMUNE MODULATING EFFECTS OF POLY ICLC - Levy - 1980

Volume 350, Issue 1 p. 33-41 Annals of the New York Academy of Sciences. IMMUNE MODULATING EFFECTS OF POLY ICLC. Hilton B. Levy,. Hilton B. Levy.

#29. Therapeutic Effect of Irreversible Electroporation in ... - JVIR

immunogenic adjuvant poly-ICLC (polyinosinic-polycytidylic acid and ... Results: Intratumoral administration of poly-ICLC immediately before IRE elicited ...

#30. Poly I:C as Vaccine Adjuvant - Creative Biolabs

Poly -ICLC. Poly-ICLC is a synthetic derivative of Poly(I:C) and also contains poly-L-lysine in carboxymethyl cellulose (CMC). It is made by a combination of ...

#31. Poly ICLC

It consists of carboxymethylcellulose, polyinosinic-polycytidylic acid, and poly-L-lysine double-stranded RNA.[1]. Poly ICLC. Combination of. Clinical data.

#32. NY-ESO-1 Protein Cancer Vaccine With Poly-ICLC and OK-432

Nonspecific activations of T-cell or antigen presenting cells were not observed. Our present study showed that poly-ICLC is a promising adjuvant ...

#33. Poly-ICLC to Prevent Respiratory Viral Infections A Safety Study

Poly -ICLC to Prevent Respiratory Viral Infections A Safety Study. NCT00646152. https://clinicaltrials.gov/show/NCT00646152, 2008 | added to CENTRAL: 31 May ...

#34. Phase 2 Trial of Poly-ICLC Vaccination for Solid Tumors

Whether poly-ICLC vaccination is safe and efficacious for patients with melanoma, head and neck cancer, sarcoma, or a non-melanoma skin ...

#35. Poly-IC enhances the effectiveness of cancer immunotherapy ...

Systemic administration of poly-ICLC elicits antitumor effects accompanied by enhanced CD8 T cell tumor infiltrates. While developing an intravenous peptide- ...

#36. API | poly-iclc - Clinical Drug Experience Knowledgebase

poly -iclc Report issue · SMILES: · InChIKey: · Mol. Mass: · ALogP: · ChEMBL Molecules: ...

#37. Poly-ICLC, a multi-functional immune modulator for treating ...

We emphasize the role of poly-ICLC as an adjuvant in the setting of peptide-based cancer vaccines and in situ tumor vaccination by mimicking natural immune ...

#38. A Novel In Situ Vaccine: Intratumoral Flt3L and Poly-ICLC with ...

A Novel In Situ Vaccine: Intratumoral Flt3L and Poly-ICLC with Low-Dose Radiotherapy ... Lymphomas are the 5 th most common cancer in the United States, 40% of ...

#39. Studies with the IFN Inducer and Immune Modulator, Poly ICLC

Borecky L, Lackovic V (eds): Physiology and Pathology of Interferon System. International Symposium, Smolenice, May 1983: Proceedings.

#40. Preliminary trial of poly ICLC in chronic progressive multiple ...

We conclude that poly ICLC can be administered safely to MS patients, and that a controlled trial will be necessary to determine efficacy.

#41. Find a Clinical Trial by Drug - poly-ICLC

Find a Clinical Trial by Drug. Adult Cancers; Childhood Cancers; Doctor; Drug; Phase. New studies open frequently, please check back for updates.

#42. Studies on poly-ICLC treatment as a potent neuroprotective ...

Studies on poly-ICLC treatment as a potent neuroprotective therapy against ischemic brain injury Public Deposited · Items ...

#43. A Study of Varlilumab and IMA950 Vaccine Plus Poly-ICLC in ...

A Study of Varlilumab and IMA950 Vaccine Plus Poly-ICLC in Patients With WHO Grade II Low-Grade Glioma (LGG). Summary. Low-grade gliomas (LGG), which include ...

#44. SNO 2020: The IMA950/Poly-ICLC Multipeptide Vaccine, With ...

SNO 2020: The IMA950/Poly-ICLC Multipeptide Vaccine, With or Without Pembrolizumab, Has Elicited T-Cell Responses in Relapsed GBM.

#45. Poly-ICLC (Hiltonol ) Vaccine In Malignant Pleural ...

To evaluate IT Poly-ICLC induced immune changes in the tumor microenvironment by comparing pre-injection biopsy to surgically resected tissue for immune cell ...

#46. poly ICLC | CTD - The Comparative Toxicogenomics Database

Name, poly ICLC. Equivalent Terms, Hiltonol | P.I.C.L.C. | poly-ICLC | poly ICLC, sodium salt | polyriboinosinic-polyribocytidylic acid-polylysine ...

#47. Combating the Threat of Pandemic Influenza: Drug Discovery ...

Poly ICLC administered 20 days prior to infection provided no protection. Route of administration was important as mice treated with two intravenous (i.v.) ...

#48. Oncovir, Inc.

We promote Hiltonol® (poly-ICLC) as an experimental viral mimic and broad activator of innate and adaptive immunity. While initially developed as an ...

#49. A Phase I trial using local regional treatment, nonlethal ...

Systemic poly-ICLC in malignant glioma patients is safe and has shown a clinical benefit. Sequential intratumoral and IM poly-ICLC led to ...

#50. CLIN CANCER RES：Poly-ICLC瘤内注射治疗实体肿瘤

poly -ICLC是一种合成的双链RNA复合物，toll样受体-3和MDA-5的配体，可激活免疫细胞（如树突状细胞），并诱导自然杀伤细胞杀死肿瘤细胞。

#51. Bioactive Polymeric Systems: An Overview - 第 411 頁 - Google 圖書結果

patient with dysimmune dysschwannian motor neuropathy who has been treated with poly(ICLC) for four years. Several months after therapy with poly(ICLC) this ...

#52. Treatment of solid tumors with intratumoral poly-ICLC - ASCO ...

Pilot studies in pediatric brain cancer have shown efficacy.1 Poly-ICLC can be given intra-muscularly (IM) to induce systemic inflammation and/or intratumorally ...

#53. method for preparation of poly-iclc and uses thereof - WIPO ...

Method for producing large lots of final sterile Poly-ICLC suitable for clinical use with reduced toxicity at effective dose levels, and method for using ...

#54. L03AX08 - WHOCC - ATC/DDD Index

... is based on the total dose devided by days of first treatment cycle (42 days). ATC code, Name, DDD, U, Adm.R, Note. L03AX08, poly ICLC ...

#55. Annual Progress Report - U. S. Army Medical Research ...

TEMPORAL PROTECTION IN HAMSTERS ( 9 / POINT ) FOLLOWING INOCULATION WITH IEEE AND GRADED DOSES OF POLY ( ICLC ) GROUP [ Poly ( ICLC ) Dose ] % SURVIVAL BY ...

#56. Annual Progress Report - 第 133 頁 - Google 圖書結果

TEMPORAL PROTECTION IN HAMSTERS ( 9 / POINT ) FOLLOWING INOCULATION WITH IEEE AND GRADED DOSES OF POLY ( ICLC ) GROUPS [ Poly ( ICLC ) Dose ] % SURVIVAL BY ...

#57. Poly-ICLC (Hiltonol®) Vaccine In Malignant Pleural ... - Smart Patients

This study will examine the safety and potential effectiveness of poly-ICLC directly injected into malignant pleural mesothelioma at the time of biopsy up ...

#58. HIV-Associated Immune Activation and Persistent Inflammation

FIGURE 6 | No changes in DC and NK cell numbers and activation following Poly-ICLC treatment. DC and NK cell subsets were enumerated as described following ...

#59. Poly ICLC - Academic Dictionaries and Encyclopedias

Poly ICLC. Drugbox IUPAC_name = CAS_number = ATC_prefix = L03 ATC_suffix = AX08 PubChem = DrugBank = chemical_formula = molecular_weight = bioavailability =

#60. Poly-ICLC (Hiltonol®) Vaccine In Malignant Pleural ... - CheckOrphan

- To evaluate IT Poly-ICLC induced immune changes in the tumor microenvironment by comparing pre-injection biopsy to surgically resected tissue for immune cell ...

#61. Der Toll-Like-Rezeptor-3-Markt wird in der Covid-19-Analyse ...

Poly -ICLC. PrEP-001. Andere. Globaler Toll-Like-Rezeptor-3-Markt nach Anwendung, 2017-2022, 2023-2028 (Millionen US-Dollar).

#62. Purple dream strain seeds. Jan 01, 2022 · Brand-new! The ...

Description: It is a poly hybrid between The Purps, Purple Urkle, Gran Daddy Purple, Grape Ape and SR71 Purple Kush, a mix of purple genetics gathered to ...